I sat down with Dr. Angela Poff, one of the top experts in the field, and it turned into a very enlightening interview.
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If you’re addicted to sugar and carbs, does that mean that you can’t eat sweets of any kind, ever?
This and other questions are answered this week by our food addiction expert, Bitten Jonsson, RN: Continue Reading →
Does intensive drug treatment of cholesterol levels lower the risk of death, compared to less intensive treatment? Not according to a review of the science. The slide above was shown at the recent American College of Cardiology conference, as tweeted by a Yale cardiologist.
This is the same negative result as shown in the first hard endpoint trial of the super-hyped PCSK9 inhibitors. They did not stop any death from heart disease either, in fact the trend was in the opposite direction.
If even more drugs is not the answer, what is? Perhaps lifestyle modification to reduce metabolic risk factors like low HDL, elevated blood sugars, high blood pressure and excess weight? If so, low carb could be a good option.
Before you start taking pills to treat your acid reflux (and risking bothersome side effects), consider changing your diet and exercise routine. It can be much more effective while bringing fewer complications:
There are studies showing that reducing the amount of carbs one eats and going low carb has a positive effect on acid reflux. So much in fact that many patients were able to quit their medications all together. Learn more here:
Imagine a new injectable drug that drops cholesterol to incredibly low levels. People thought it might result in a virtual immunity from heart disease, thus pricing them at an astonishing $14,000 per patient, per year.
There was only one problem – there was no proof that the drug actually did anything good except lowering cholesterol.
The new drug evolocumab, a PCSK9 inhibitor, has still been called a huge advancement in the battle against heart disease and stroke. This exclusively because of its ability to dramatically lower the “bad” LDL cholesterol. The question is whether this truly is a revolutionary advancement for people’s health – or not?
Now we know. Continue Reading →
Are cholesterol-lowering statin drugs proven to be very safe and effective? Is it time to stop even debating this? Or is this just what the pharmaceutical industry wants you to believe?
Fiona Godlee, editor-in-chief of the British Medical Journal, has a strong point of view:
Questions about the evidence base for statins continue to emerge from many quarters: how strong is the evidence, how large is the benefit for individuals at lowest risk of heart disease, how well did the trials record common minor side-effects, how representative were the trials of women and the elderly, what was the effect of active run-in periods and composite endpoints, how does taking a statin affect a person’s diet and exercise patterns, why is there a discrepancy between the real-life experience of muscle pain and what was reported in the trials, why have the data for harms not yet been given the same levels of scrutiny as the data for benefits, and is cholesterol a reliable surrogate endpoint to guide prevention of cardiovascular disease?
So despite Horton and Collins and colleagues wanting to shut down the discussion and award themselves the final word, the debate about statins in primary prevention is alive and kicking. It is a debate that needs to be resolved as thoughtfully, objectively, and openly as possible, and not by eminence-based narrative reviews, however extensive, based on meta-analysis of data that only Collins, his fellow trialists, and industry sponsors have seen.
– Fiona Godlee
4.7 out of 5 stars5 stars91%4 stars1%3 stars1%2 stars1%1 star4%69 ratings907 viewsDavid Diamond’s doctor told him to go on statins because of high cholesterol. But David wanted to make sure that he knew the science before starting the medication. He started reading, and quickly realized that what we think we know about cholesterol, heart disease and statins is not quite right.
With his new knowledge, he became highly interested in the field and was able to make vast improvements – without ever taking medications.
Watch a segment above (transcript). The full, longer video is available on our member site:
Cristina met many physicians who urged her to lose weight for the sake of her fatty liver, pre-diabetes and PCOS – but with no hint on how to do it. She’d be able to lose some weight, but yo-yoed back up in no time.