A comprehensive guide to salt
“The salt of the earth.” “Worth one’s salt.” “Salt away” savings. These age-old expressions illustrate the value humans have placed on salt for eons.
More recently, however, salt has gone from something treasured to something feared. Health authorities have been encouraging us for decades to cut back on this once-prized substance, especially for lowering blood pressure and decreasing heart disease risk.
But are low-sodium diets necessary — or even safe — for everyone? Read on to learn more about salt and how much of it we should be eating, based on the best current evidence.
This guide is written for adults eating a low-carb diet who are concerned about salt intake and health.
Discuss any lifestyle changes with your doctor. Full disclaimer
1. What is salt?
When you hear the word “salt,” you probably picture a typical salt shaker filled with the white, crystalline substance that’s added to food for seasoning purposes. Originating from seawater, evaporated lakes, or mines deep beneath the earth, salt not only brings out flavors in foods, but it’s also used as a preservative and plays an important role in curing, smoking, pickling, and processing food.
For centuries, salt was a precious commodity that was traded for gold. In fact, the term “salary” comes from salarium, the Latin word for salt.
Salt vs. sodium: What’s the difference?
Although frequently used interchangeably, salt and sodium aren’t the same thing — an important distinction when discussing daily intake. Sodium is a mineral that is found naturally in small amounts in many foods such as meat, milk, yogurt, certain tropical fruits, and vegetables like artichokes, celery, beets, and seaweed.
Salt is sodium combined with chloride, another mineral. Since sodium chloride is roughly 40% sodium, 5 grams of salt (about 1 teaspoon) contains about 2 grams of sodium. According to one study, salt added to processed foods accounts for about 70% of our daily sodium intake.3
Some sodium also comes from baking soda (sodium bicarbonate) in baked goods, crackers and cookies.
In short, sodium is the essential mineral our body uses, but salt (sodium chloride) is the dominant way we ingest that mineral.
Different types of salt
Salt is found on every continent, and edible forms are available in dozens of varieties. Here are a few of the most popular:
- Table salt: Known as rock salt, or halite, it is mined from underground deposits resulting from the evaporation of ancient seas. Rock salt can be used for curing meat or pulverized to a fine texture to create table salt. To prevent goiter and other problems caused by iodine deficiency, manufacturers typically add iodine and label their salt as iodized.
- Sea salt: Coarser-grained, flakier, and more subtly flavored than table salt, sea salt comes from evaporated present-day seawater. It may sometimes contain natural traces of iodine.
- Himalayan salt: Harvested from salt caves in the Himalayan mountains of Pakistan, this colorful salt ranges from off-white to deep pink and contains minuscule amounts of trace minerals despite common claims of larger amounts.
- Kosher salt: Its large size and coarse texture is used in the koshering process to draw fluids out of meat. Kosher salt is never iodized.
Although some forms are less processed than others and differ slightly in taste and trace mineral content, from a nutritional point of view, salt is salt, or sodium chloride (NaCl). Most salt substitutes are a mix of sodium chloride and potassium chloride (KCL).
2. Why do we need salt?
Sodium is an essential nutrient that must come from your diet because your body can’t make it on its own. As the most concentrated electrolyte in your blood, sodium helps:4
- maintain the delicate chemical and fluid balance in and around your cells
- maintain blood pressure
- contract muscles
- conduct nerve impulses
Sodium levels in your body are tightly regulated by your kidneys, central nervous system, and adrenal glands to make sure it doesn’t go too high or too low. In fact, normal dietary fluctuations in sodium intake will usually have no effect on the concentration of sodium in your blood.5
3.The controversy over salt intake
What is a “healthy” daily sodium intake? It seems like a simple question, yet it’s one that’s generated quite a bit of controversy over the past several decades.
According to major health organizations in the US and Europe, nearly all of us consume too much sodium on a regular basis, mainly from processed foods.6 They recommend that we sharply reduce our sodium consumption in order to prevent high blood pressure and decrease the risk of heart disease and kidney disease, down to the equivalent of just 1 teaspoon of salt per day.
- For instance, the 2015-2020 Dietary Guidelines for Americans specify that people should eat no more than 2.3 grams (2,300 mg) of sodium per day — the equivalent of about 1 teaspoon.
- The American Heart Association goes even further, saying that everyone should ideally consume less than 1,500 mg of sodium (approximately ¾ of a teaspoon) daily. Most people would consume that much by just eating a bowl of soup or a Caesar salad.
- The World Health Organization (WHO) recommends that we cap our salt intake at 5 grams of salt per day, which at first glance seems quite a bit higher than the amounts above. However, remember that salt is only 40% sodium. Therefore, the WHO’s guidelines call for limiting sodium to 2,000 mg per day.
Other experts have also been saying that too-low sodium intake may have unintended adverse health consequences.8 Let’s dive deeper into this controversy, by reviewing the evidence.
The salt guidelines are too restrictive, say experts
News Is it really necessary to lower your salt intake as much as the current guidelines advise, in order to lower your blood pressure? According to a new expert paper, the guidelines are way too restrictive and not based on enough evidence.
4. Research on salt intake in healthy adults
Is there any evidence that following a low-sodium diet, when healthy, can help decrease your risk of developing chronic disease or dying? The answer may surprise you.
Systematic reviews and meta-analyses of RCTs from 1996, 2011, and 2017 all showed no benefit of salt restriction among people with normal blood pressure.9 A 2014 Cochrane review likewise showed no mortality benefit from salt restriction.10
Further, a 2019 meta-analysis of meta-analyses and RCTs from Annals of Internal Medicine confirmed the lack of any effect of salt restriction on all-cause mortality and cardiovascular mortality, although the certainty of evidence was deemed to be low.11
One large 2020 observational study, which constitutes a weaker level of evidence, nonetheless showed that higher sodium intake correlated with longer life expectancy and decreased all-cause mortality.12
With meta-analyses of RCTs showing no benefit to salt restriction and some observational data showing better life expectancy with greater salt intake, can we consider the issue settled?
Unfortunately, no. Many observational studies and RCTs have consistently shown that sodium reduction lowers blood pressure, considered a surrogate marker for the risk of problems like heart attack and stroke. And some studies have shown an improvement in cardiovascular risk with reduced sodium intake.13
Nevertheless, when evaluating the entirety of the evidence, we believe it is important to note that small reductions in blood pressure do not consistently track with a reduced risk of the hard endpoints we care about, like heart attack, stroke, and death.14
Based on all available data, it seems likely that there is a U-shaped relationship between salt intake and disease or death, with elevated risks at the very lowest and very highest intakes.
Could limiting salt actually harm healthy individuals?
As we said above, we believe that there may be excess risk at the very lowest and highest intakes of sodium, but the data are mixed.
One group of researchers conducted a review of both observational studies and RCTs and concluded that sodium restriction has no detrimental effects in healthy people and could potentially benefit some people. Therefore, they feel a low-salt diet is advisable for all.15
This finding was questioned by the PURE study, which reviewed data on sodium intake from over 100,000 people living in 17 countries. This study found that excreting less than 3,000 mg of sodium per day was associated with an increased risk of heart attack and death in people whether or not they already had elevated blood pressure.16 The lowest risk was between 3,000mg and 7,000mg daily excretion, assumed to correlate with intake.
In earlier analyses by the same researchers, consuming between 3 and 6 grams of sodium daily was linked to the lowest risk of heart disease and early death.17
While observational data like this cannot prove that sodium intake is either a risk factor or a protective factor for heart disease, it does suggest that diets with 3 to 6 grams of salt a day could be part of a healthy lifestyle. For more discussion about this, listen to cardiologist and Diet Doctor’s medical director Dr. Bret Scher discuss the PURE study findings with one of its principal investigators Professor Andrew Mente.
In 2017, a coalition of three European health organizations recommended an upper limit of 5,000 mg of sodium per day for most people — more than twice as much as the 2,300 mg guidelines that come from other major health organizations.20
Again, given the evidence for a U-shaped relationship between sodium intake and the risk of health problems, we believe that healthy people will likely not benefit from significant sodium restriction. Likewise, when following a standard Western diet, it seems advisable to keep sodium intake moderate to avoid excess risk.
As for those following low-carbohydrate or ketogenic diets, we don’t know if the available evidence applies; click the green button below to explore the nuance.
With decreased carb intake, insulin levels fall significantly. It’s been known for decades that when insulin levels drop, the kidneys excrete more sodium and water.21
If sodium isn’t replaced, you’re likely to develop the unpleasant symptoms of “keto flu,” which include headache, fatigue, and weakness.
What’s more, a keto or low-carb diet composed of mainly whole foods doesn’t have a lot of sodium to begin with, especially compared to processed foods. Thus some may want to add more salt to avoid side effects.22
How can we reconcile advising increased salt intake when we just mentioned that some trials have shown a small mortality benefit with salt reduction? This is where we need to more closely consider the dietary composition of the typical study participant.
In a standard Western diet, much of the sodium comes from processed foods that tend to be high in refined carbohydrates and sugars.23 This type of diet often leads to higher insulin production by the pancreas and, as we’ve already explained, one of the downstream effects of higher insulin levels is reabsorption of sodium by the kidney.
On a low carb, whole foods diet, however, insulin levels are typically lower, leading to less reabsorption of sodium by the kidney (i.e. more sodium is excreted in the urine). Therefore, it is possible that people eating low-carb or ketogenic diets may be able to ingest more salt than someone eating a standard Western diet, as they may be better able to excrete the excess into the urine.24
Although we postulate this based on sound mechanistic logic, we also recognize that there are multiple pathways by which the body can maintain sodium balance. We simply do not know if the tendency of lower insulin levels to lead to sodium excretion will be counteracted by other pathways that cause the body to hold on to sodium. But we believe that adding sea salt to your roasted veggies and steak in the context of a low-carb diet is likely different than eating salt that comes with ultra-processed and packaged foods.
Since we don’t have long term data showing safety, we are cautious in our recommendation to increase salt intake, especially for those with underlying medical conditions.
See Section 5 below for more information regarding salt and co-existing medical issues.
Ways to increase salt intake – more info
Consuming about 4,000 to 7,000 milligrams of sodium (about 2 to 3 teaspoons of salt) is usually sufficient to get through keto-adaptation and can often be maintained beyond the transition period, depending on individual needs.25
Here are a few ways to boost sodium intake. However, if you have elevated blood pressure, kidney disease or congestive heart failure, talk to your doctor first before increasing your sodium intake, especially if you take medication.26
- Drink 1 or more cups of salty broth every day
- Add 1-2 teaspoons of salt in daily food preparation or at the table
- Eat olives, pickles, sauerkraut, and other salty keto foods regularly
- Choose standard rather than “low-sodium” sauces and seasonings for cooking
- Shake salt into a glass of water a couple of times a day.
5. What about salt intake in people with medical conditions?
Recommendations to reduce sodium intake are so pervasive that one could assume the research must consistently demonstrate that low-sodium diets markedly improve various medical conditions. In truth, the effect of sodium restriction is often more modest than one would think; plus, much of the evidence has been contradictory or inconclusive.
Let’s take a closer look at the evidence for salt restriction as it relates to common chronic diseases:
Hypertension is the medical term for high blood pressure. It currently affects almost one in three people and is especially common in older, overweight or obese individuals.27 See our guides on high blood pressure and what you can do about it for more information.
Is there overwhelming evidence that salt restriction significantly lowers blood pressure for everyone? No, not really, for a few reasons:
- Not everyone is salt sensitive. Eating a lot of sodium doesn’t significantly raise blood pressure in everyone, including those with hypertension. A person whose blood pressure increases after eating salt is said to have “salt-sensitive hypertension.”28
It’s estimated that about 50% of those with hypertension and 25% of individuals with normal baseline blood pressure are salt sensitive, meaning their systolic blood pressure increases by at least 5 points following a high-sodium diet compared to a low-sodium diet.29Therefore, higher sodium intake may not increase blood pressure in about half of all people with hypertension. As we discuss next, salt restriction will also not lower blood pressure in this population.
- Reducing sodium intake may decrease blood pressure, but only slightly. The highest quality data have found that for most hypertensive adults, sodium restriction doesn’t lead to a dramatic decrease in blood pressure.30
In practical terms, going from 3,500 mg to 1,500 mg of sodium per day might reduce systolic blood pressure by an average of 5 points. Although this modest change may be viewed as a statistically significant reduction in risk by researchers, individuals may question if sustaining this level of sodium restriction is worth the effort and inconvenience.
Could this small reduction in blood pressure explain the small reduction in cardiovascular mortality seen in two meta-analyses of RCTs? It is possible. It is also possible that the smaller percentage of people who are salt sensitive had a greater effect, and thus saw an improvement in mortality. Unfortunately, the data do not specify this degree of detail.
- Sodium restriction may have adverse effects. Cutting back on salt may have a negative impact on other health markers in hypertensive adults.
In a very large review of 185 clinical studies, people with hypertension who followed a sodium-restricted diet for two or more weeks experienced a 3.5% decrease in blood pressure, on average.31However, this came at the expense of an increase in triglycerides and in the adrenal hormones aldosterone, adrenaline and noradrenaline, which could potentially lead to health problems over time.
What’s more, the response to sodium restriction in hypertensive individuals seems to include increased insulin resistance, regardless of whether they are salt sensitive.32
It is therefore important to realize that salt reduction is not without potential adverse effects, thus making general population recommendations more challenging.
- Overall diet may affect blood pressure as much as salt does. Other researchers have suggested that rather than restricting sodium intake, those who are salt sensitive should be provided with tools to improve the quality of their diet, promote weight loss, and decrease insulin resistance, which could help make them less salt sensitive and reduce their disease risk.33 While it may not be the only beneficial approach, a very-low-carbohydrate, ketogenic diet may significantly decrease blood pressure in those who are overweight or have metabolic syndrome, regardless of the diet’s sodium content.34
How to normalize your blood pressure
GuideElevated blood pressure is a common health issue today. Almost a third of U.S. adults have high blood pressure – perhaps you or someone in your family does? High blood pressure isn’t necessarily something you can feel, but it increases the risk of serious conditions such as strokes and heart attacks.
Heart disease, also known as cardiovascular disease (CVD), is a broad term that includes several disorders. People with CVD are generally advised to reduce their salt consumption as part of a “heart healthy diet,” but here is what the research has found:
A systematic review and meta-analysis of 11 randomized controlled trials (RCTs) concluded that reducing sodium by an average of 3,000 mg per day improved arterial elasticity.36 By contrast, several large observational studies have found that very low sodium intake is associated with worse cardiovascular outcomes.37
While these associational data do not prove cause and effect, it has been hypothesized that the poor outcomes are due to the aldosterone and adrenaline increases discussed previously. Of course, we need to balance these observational studies with those mentioned previously that do show a small reduction in cardiovascular outcomes.
At a minimum, the lack of RCT hard outcome data and the contradictory observational studies should trigger a healthy dose of skepticism that reducing salt intake is necessary for reducing the risk of heart attack.
- Congestive heart failure:38 Individuals with CHF are usually told to minimize sodium intake in order to prevent fluid overload.
However, this seems to be based mostly on longstanding clinical dogma and experience, without the backing of strong research.
In fact, in 2018, investigators performed a systematic review of nine RCTs and concluded that there isn’t enough high-quality evidence to either support or refute the benefit of sodium restriction for CHF.39 And a 2022 RCT reported no difference in clinical events with very low or standard sodium intake.40
As a result, some in the medical community are rethinking whether patients with CHF benefit from very-low-sodium diets.41
Based on inconsistent results across studies, it’s possible that some people may be more sensitive to sodium’s fluid-retaining effects than others. Although more research is needed, individualized sodium recommendations, as opposed to the application of general guidelines, may be most appropriate for managing CHF.
Diabetes and prediabetes
Since people with diabetes are at increased risk for both heart and kidney disease, they are usually advised to limit their salt intake. At one time, the American Diabetes Association recommended that individuals with diabetes aim for less than 1,500 mg of sodium per day; however, this was modified to 2,300 mg per day in the 2019 Standards of Care in Diabetes based on the lack of evidence supporting further restriction.
Overall, the evidence to date seems to suggest that salt restriction doesn’t improve diabetes outcomes.
- Observational studies suggest potential increase in heart disease and mortality risk. One 2011 study found that people with type 2 diabetes who consumed the least sodium had an increased risk of early death from heart disease or other causes compared to those who consumed the most sodium.42 Another 2011 study in people with type 1 diabetes reported that both the highest and lowest intakes of sodium were linked to an increased risk of early death and developing kidney disease.43
- Experimental study outcomes are mixed. Of the few RCTs available, some have found that sodium restriction may lead to small improvements in blood pressure and kidney function in people with type 2 diabetes.44
High-quality research on salt restriction in type 1 diabetes is even more scarce, but two small studies suggest that restricting salt may have adverse effects on kidney health.45
Although a meta-analysis of RCTs in people with type 1 and type 2 diabetes found that sodium restriction helped reduce blood pressure, the largest effects were seen in people with normal blood pressure, for whom further blood pressure reduction might be of limited or no value. In addition, the median duration of salt restriction was one week; we know from longer trials that the effect of salt restriction on reducing blood pressure tends to wane over time.46
- Health risks of high sodium intake may depend on blood sugar control. One study in Japanese men with type 2 diabetes found an association between higher sodium intakes and greater heart disease risk, but this only applied to those with extremely poor diabetes control (HbA1c of 9% or greater); no relationship was found between high salt intake and CVD in those with lower HbA1c’s.47
- Increased insulin resistance: Controlled studies have found that eating too little salt may worsen insulin resistance in adults with type 2 diabetes or exacerbate impaired glucose tolerance in people with prediabetes.48 Remember that sodium restriction may triggers the adrenal glands to release aldosterone and noradrenaline, which may lead to reduced insulin sensitivity.49
In short, avoiding very high sodium intakes greater than 6 grams a day (15 grams of salt) may be beneficial for people with diabetes who have salt-sensitive hypertension. Sodium restriction in everyone else with diabetes, however, is less proven and has the potential to do more harm than good.
The National Kidney Foundation advises people with kidney disease to limit their sodium intake to less than 2,000 mg per day.50 However, the optimal sodium restriction for people with chronic kidney disease isn’t clear.
A recent meta-analysis of RCTs found that sodium restriction in people with early to end-stage kidney disease can significantly lower blood pressure and reduce urinary albumin.51
And an observational study found that consuming more than 4,500 mg of sodium daily (11 grams of salt) was associated with increased risk of CVD, heart attack, and stroke in people with chronic kidney disease. A wide range of sodium intakes below this level were all linked to lower risk.52
Therefore, for this group, moderate sodium restriction – below four grams per day – may be beneficial. Moreover, this level of sodium intake may be easier to sustain than some of the more extreme targets for salt restriction that have been proposed.
6. Is salt the real culprit?
According to health organizations, high amounts of sodium in processed foods have played a major role in the epidemics of heart disease and other cardiometabolic conditions. In addition, analyses of RCTs suggest a benefit from reducing salt consumption.
However, what if it isn’t the sodium but rather the sugar and refined carbs that are responsible for most of the effects of highly-processed food? Unfortunately, the research does not do a great job of teasing this out.
Some researchers have suggested that sugar rather than sodium is the main driving force in hypertension, while others say that it’s a combination of sugar and salt.53 However, most studies have a hard time separating overall salt intake from consumption of these potentially unhealthy processed foods.
In addition, it’s important to remember that diets higher in carbs and sugars lead to higher insulin levels, and higher insulin levels cause more sodium retention by the kidneys. Therefore, it’s quite possible that the amount of sodium we consume becomes more important as we consume more carbohydrates, and less important as we move toward a low-carbohydrate diet.
We know that reducing carbs can lower blood pressure, decrease CVD markers, help reverse diabetes, and promote weight loss — even with moderate to high sodium consumption.54 So the focus on the sodium content in processed foods alone may be somewhat misleading.
Higher potassium intake is well-known to correlate with lower blood pressure, even at higher levels of sodium intake.55
Some studies suggest that the sodium-to-potassium ratio is better at predicting cardiovascular disease and death than the intake of either nutrient alone.56
It’s not clear if the observed benefit of increasing potassium is entirely due to potassium versus other beneficial substances found in potassium-rich foods.57 But potassium itself clearly contributes to lowering blood pressure, given the positive findings of a meta-analysis of RCTs that studied the use of potassium pills in hypertension.58
How much potassium must one consume to see blood pressure-lowering effects? Although the United States recommended intake for this purpose is 4700mg, there appears to be good evidence for substantial benefit starting around 3500mg.59
Given the fact that a standard Western diet tends to be very low in potassium-rich foods (e.g. fruits and vegetables) and very high in sodium, it is conceivable that some of the harm attributed to excessive sodium is actually attributable to insufficient potassium consumption.60
And, have you heard the advice that you should eat more bananas to get more potassium? Don’t do it! These foods are healthier choices for potassium-rich foods.
Beans or lentils
7. Summary: How much salt should you eat?
Both published research and anecdotal evidence have shown that the response to salt intake varies from person to person.61
If you have salt-sensitive hypertension, congestive heart failure, or kidney disease, it may be best to avoid eating more than four grams of sodium per day. However, the amount that’s best for you may require some experimentation, in coordination with your medical provider. Also, keep in mind that eating a high-quality, carb-restricted diet may potentially improve blood pressure, cardiovascular function, and kidney health much more than restricting salt.
If you don’t have any of these conditions, there isn’t any convincing evidence that sodium restriction is beneficial when following a minimally processed low-carb diet.
Consuming about 4 to 7 grams of sodium (about 2 to 3 teaspoons of salt) per day is where many people in the low-carb community will feel and perform the best.62 Occasionally, you may need to further increase sodium intake to replenish salt losses during the first few weeks of a ketogenic diet, during hot weather, or after strenuous physical activity. Just keep in mind that if you have salt-sensitive hypertension, you will need to be more cautious than most.
Finally, remember that it’s always good advice to replace highly-processed, low-quality food with minimally-processed, nutritious food. On that, we can all agree.
A comprehensive guide to salt - the evidence
This guide is written by Franziska Spritzler, RD and was last updated on September 28, 2022. It was medically reviewed by Dr. Michael Tamber, MD on September 9, 2021 and Dr. Bret Scher, MD on September 28, 2022.
The guide contains scientific references. You can find these in the notes throughout the text, and click the links to read the peer-reviewed scientific papers. When appropriate we include a grading of the strength of the evidence, with a link to our policy on this. Our evidence-based guides are updated at least once per year to reflect and reference the latest science on the topic.
All our evidence-based health guides are written or reviewed by medical doctors who are experts on the topic. To stay unbiased we show no ads, sell no physical products, and take no money from the industry. We're fully funded by the people, via an optional membership. Most information at Diet Doctor is free forever.
Read more about our policies and work with evidence-based guides, nutritional controversies, our editorial team, and our medical review board.
Should you find any inaccuracy in this guide, please email email@example.com.
A Cochrane meta-analysis of RCTs shows no clear benefit:
Cochrane 2014: Reduced dietary salt for the prevention of cardiovascular disease [strong evidence]
An earlier Cochrane review found a significantly increased risk of death from salt restriction in people with heart failure:
American Journal of Hypertension 2011: Reduced dietary salt for the prevention of cardiovascular disease: a meta-analysis of randomized controlled trials (Cochrane review) [strong evidence] ↩
Obesity Reviews 2009: Systematic review of randomized controlled trials of low-carbohydrate vs. low-fat/low-calorie diets in the management of obesity and its comorbidities [strong evidence] ↩
Circulation 2017: Sources of sodium in US adults from 3 geographic regions [observational study; very weak evidence] ↩
Electrolytes are minerals that form positive or negative electrical charges when dissolved in blood and other body fluids. The major electrolytes are sodium, potassium, calcium, magnesium, and phosphorous. See Diet Doctor guide: Do you need electrolyte supplementation on a keto diet ↩
American Journal of Physiology 2003: Body sodium and volume homeostasis [overview article, ungraded] ↩
Surveys show that adults in the US consume about 3-4 grams of sodium per day, on average, with almost 90% eating more than the recommended amounts.
CDC 2016: Prevalence of Excess Sodium Intake in the United States — NHANES, 2009–2012 ↩
European Heart Journal 2020: Salt and cardiovascular disease: insufficient evidence to recommend low sodium intake [overview article; ungraded]
QJM: Monthly Journal of the Association of Physicians 2011: Should we now abandon the low-salt diet? [commentary article; ungraded] ↩
We explore this further in our post:
The salt guidelines are too restrictive, say experts
Much of this concern comes from multiple studies showing an increase in the hormones renin and aldosterone and their potential negative downstream effects.
JAMA 1998: Effects of sodium restriction on blood pressure, renin, aldosterone, catecholamines, cholesterols, and triglyceride [systematic review of randomized trials; strong evidence]
Journal of the American Medical Association 1996: Effect of reduced dietary sodium on blood pressure: a meta-analysis of randomized controlled trials [strong evidence]
American Journal of Hypertension 2011: Reduced dietary salt for the prevention of cardiovascular disease: a meta-analysis of randomized controlled trials (Cochrane review) [strong evidence]
Cochrane Systematic Review 2017: Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride [systematic review of randomized trials; strong evidence]
Cochrane Database of Systematic Reviews 2014: Reduced dietary salt for the prevention of cardiovascular disease [systematic review of RCTs; strong evidence]
There was no statistically significant difference in all-cause mortality or cardiovascular mortality. The authors concluded, however, that there was “weak evidence” for improved cardiovascular mortality. The relative risk of CV mortality with salt restriction was 0.67, but the confidence interval was wide and crossed 1.0 (0.45-1.01), making this statistically insignificant. Therefore, the more accurate conclusion is that the data did not show a significant difference in cardiovascular mortality. ↩
Although the original paper found a mild benefit of salt restriction in certain subgroups, the authors published a correction to their paper with an updated statistical analysis that they believe more accurately reflects the conclusions that can be drawn from the available evidence. Their corrected analysis shows no benefit of salt restriction on mortality in normotensive or hypertensive people.
Annals of Internal Medicine 2019: Effects of nutritional supplements and dietary interventions on cardiovascular outcomes: An umbrella review and evidence map [systematic review of RCTs; strong evidence] ↩
This study collected data from 181 countries and found that sodium intakes up to 4-5 grams/day (salt intake 10-12.5 grams/day) correlated with increased life expectancy. Beyond those intakes, there was a slight decrease in life expectancy, suggesting a U-shaped relationship between sodium intake and mortality.
European Heart Journal 2020: Sodium intake, life expectancy, and all-cause mortality [nutritional epidemiology study; very weak evidence]
In addition, this 2011 observational study showed that people with the lowest urine sodium excretion (urine sodium levels correlate directly with sodium intake) had higher cardiovascular mortality.
Journal of the American Medical Association 2011: Fatal and nonfatal outcomes, incidence of hypertension, and blood pressure changes in relation to urinary sodium excretion [observational study with HR < 2; very weak evidence]↩
Cochrane Database of Systematic Reviews 2020: Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride [systematic review of controlled trials; strong evidence]
Circulation 2014: Lower levels of sodium intake and reduced cardiovascular risk[randomized trial; moderate evidence]
This meta-analysis of observational studies showed a 23% greater risk of stroke for an average difference in salt intake of 5 grams (1 teaspoon). The risk of cardiovascular disease only reached statistical significance when one outlier study was excluded from the analysis.
BMJ 2009: Salt intake, stroke, and cardiovascular disease: meta-analysis of prospective studies [very weak evidence] ↩
Several studies have shown reductions in blood pressure with sodium restriction, but not necessarily a concomitant decrease in the hard endpoints of stroke, heart attack and mortality.
In this large observational study, stroke risk only correlated with sodium intake among those with the very highest intake. On the other hand, higher sodium intakes correlated with a lower risk of heart attack and mortality.
Lancet 2018: Urinary sodium excretion, blood pressure, cardiovascular disease, and mortality: a community-level prospective epidemiological cohort study [observational study, very weak evidence] ↩
However, they acknowledged that “There were insufficient randomized controlled trials to assess the effects of reduced sodium intake on mortality and morbidity.” Therefore they based their conclusions only on the observational cohort studies, a weaker level of evidence.
The British Medical Journal 2013: Effect of lower sodium intake on health: systematic review and meta-analyses [moderate evidence] ↩
The study also found those who excreted more than 7,000 mg of sodium per day and had pre-existing high blood pressure had an increased risk of heart attack and death. This is referred to as a “U-shaped curve” where the risk increases at both high and low intake levels and is lower in the middle.
The Lancet 2016: Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies [observational study with HR < 2; very weak evidence] ↩
The New England Journal of Medicine 2014: Urinary sodium and potassium excretion, mortality, and cardiovascular events [observational study with HR < 2; very weak evidence]
Journal of the American Medical Association 2011: Urinary sodium and potassium excretion and risk of cardiovascular events [observational study with HR < 2; very weak evidence] ↩
The American Journal of Medicine 2013: Dietary sodium restriction: take it with a grain of salt [commentary; no evidence]
Journal of Nutritional Science and Vitaminology 2018: Dietary salt (sodium chloride) requirement and adverse effects of salt restriction in humans [non-controlled trial; weak evidence] ↩
Metabolism 2011: Low-salt diet increases insulin resistance in healthy subjects [randomized controlled trial; moderate evidence]
Clinical Science 2007: Salt intake and insulin sensitivity in healthy human volunteers [non-controlled trial; weak evidence]
Clinical Science 2003: Decreased insulin sensitivity during dietary sodium restriction is not mediated by effects of angiotensin II on insulin action [randomized trial; moderate evidence]
Sodium restriction signals the adrenal glands to release aldosterone, prompting the kidneys to hold on to sodium. Researchers have suggested that these higher aldosterone levels coupled with release of the stress hormone noradrenaline may be responsible for decreased insulin sensitivity in people who follow low-salt diets.
Clinical Science 2007: Salt intake and insulin sensitivity in healthy human volunteers [non-controlled trial; weak evidence]
European Heart Journal 2017: The technical report on sodium intake and cardiovascular disease in low- and middle-income countries by the joint working group of the World Heart Federation, the European Society of Hypertension and the European Public Health Association [overview article; ungraded] ↩
American Journal of Physiology. Renal Physiology 2007: Insulin’s impact on renal sodium transport and blood pressure in health, obesity, and diabetes [overview article; ungraded]
Diabetalogia 1981: The effect of insulin on renal sodium metabolism [overview article; ungraded] ↩
This is based on clinical experience of low-carb practitioners and was unanimously agreed upon by our low-carb expert panel. You can learn more about our panel here [weak evidence]. ↩
BMJ Open 2016: Ultra-processed foods and added sugars in the US diet: evidence from a nationally representative cross-sectional study [observational study, weak evidence] ↩
This is based on clinical experience of low-carb practitioners and was unanimously agreed upon by our low-carb expert panel. You can learn more about our panel here [weak evidence]. ↩
This is based on the consistent clinical experience of doctors regularly providing patients with low-carb nutrition interventions.[weak evidence] ↩
If you need assistance finding a doctor familiar with low-carb nutrition, you can look on our Find a Clinician Map. ↩
Blood pressure that remains elevated throughout the day can damage your arteries and increase the risk of heart attack, stroke, kidney disease, loss of vision, and other serious medical problems.
People with hypertension are usually put on medication and advised to minimize salt intake based on several studies suggesting that higher sodium intake may raise blood pressure.
Hypertension 2000: National Heart, Lung, and Blood Institute Workshop on Sodium and Blood Pressure: A critical review of current scientific evidence [overview article; ungraded]
British Medical Journal 1988: Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. Intersalt Cooperative Research Group [observational study with HR < 2; very weak evidence] ↩
This is due to a combination of genetic and environmental influences on the complex systems that regulate the body’s sodium balance.
Journal of the American Society of Nephrology 2014: Mechanism of salt-sensitive hypertension: focus on adrenal and sympathetic nervous systems [overview article; ungraded]
Physiological Genomics 2018: GNAI2 polymorphic variance associates with salt sensitivity of blood pressure in the Genetic Epidemiology Network of Salt Sensitivity study [mechanistic study; ungraded] ↩
Current Opinion in Nephrology and Hypertension 2012: Mechanisms and consequences of salt sensitivity and dietary salt intake [overview article; ungraded] ↩
The British Medical Journal 2002: Systematic review of long-term effects of advice to reduce dietary salt in adults [strong evidence]
Global Heart 2015: A meta-analysis of dietary salt restriction on blood pressure in Chinese adults [strong evidence] ↩
Cochrane Database of Systematic Reviews 2017: Effects of low sodium diet versus high sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride [systematic review of controlled trials; strong evidence] ↩
Hypertension 2014: Effect of low salt diet on insulin resistance in salt-sensitive versus salt-resistant hypertension [randomized controlled trial; moderate evidence] ↩
Journal of the American College of Nutrition 2006: Salt sensitivity, a determinant of blood pressure, cardiovascular disease and survival [overview article; ungraded] ↩
Journal of Medicinal Food 2011: A pilot study of the Spanish Ketogenic Mediterranean Diet: an effective therapy for the metabolic syndrome [non-randomized trial; weak evidence]
High Blood Pressure and Cardiovascular Prevention 2015: Middle and long-term impact of a very-low-carbohydrate ketogenic diet on cardiometabolic factors; a multi-center, cross-sectional, clinical study [non-randomized trial; weak evidence] ↩
The most common type of cardiovascular disease is coronary artery disease due to atherosclerosis, a process in which plaque builds up in the walls of the arteries, restricts blood flow, and increases heart attack risk. ↩
However, with the exception of one study in 169 hypertensive individuals, the studies were fairly small (between 6 and 40 participants), lasted only one to six weeks, and provided no data on clinical outcomes such as heart attacks and strokes. Therefore, the study did not address long-term effects of sodium restriction on arterial health.
Journal of Hypertension 2018: Effect of dietary sodium restriction on arterial stiffness: systematic review and meta-analysis of the randomized controlled trials [strong evidence] ↩
Journal of the American Directors Association 2018: Association between sodium excretion and cardiovascular disease and mortality in the elderly: a cohort study [observational study with HR < 2; very weak evidence]
Hypertension 1995: Low urinary sodium is associated with greater risk of myocardial infarction among treated hypertensive men [observational study with HR < 2; very weak evidence]
This showed increased cardiovascular events and death in hypertensive patients with high salt intake, but no increased risk for normotensive patients. Low salt intake was associated with an increased risk of cardiovascular events and death in everyone, regardless of whether they had hypertension.
The Lancet 2016: Associations of urinary sodium excretion with cardiovascular events in individuals with and without hypertension: a pooled analysis of data from four studies [observational study with HR < 2; very weak evidence]↩
In congestive heart failure (CHF), the heart’s ability to pump blood is impaired, leading to fluid buildup in the lungs and extremities. ↩
Journal of the American Medical Internal Medicine 2018: Reduced salt intake for heart failure: a systematic review [strong evidence] ↩
Lancet 2022: Reduction of dietary sodium to less than 100 mmol in heart failure (SODIUM-HF): an international, open-label, randomised, controlled trial[moderate evidence] ↩
Arquivos Brasileiros de Cardiologia 2010: Is the low-sodium diet actually indicated for all patients with stable heart failure? [randomized controlled trial; moderate evidence]
JACC. Heart Failure 2016: Impact of dietary sodium restriction on heart failure outcomes [observational study with HR < 2; very weak evidence] ↩
Although this does not prove it was the salt restriction that led to the increased risk, there was an association.
Diabetes Care 2011: Dietary salt intake and mortality in patients with type 2 diabetes [observational study with HR < 2; very weak evidence] ↩
Diabetes Care 2011: The association between dietary sodium intake, ESRD, and all-cause mortality in patients with type 1 diabetes [observational study with HR < 2; very weak evidence] ↩
The Lancet 2018: Moderate salt restriction with or without paricalcitol in type 2 diabetes and losartan-resistant macroalbuminuria (PROCEED): a randomised, double-blind, placebo-controlled, crossover trial [moderate evidence]
Hypertension 2016: Modest salt reduction lowers blood pressure and albumin excretion in impaired glucose tolerance and type 2 diabetes mellitus: a randomized double-blind trial [moderate evidence] ↩
Diabetologia 2002: Short-term moderate sodium restriction induces relative hyperfiltration in normotensive normoalbuminuric Type I diabetes mellitus [randomized trial; moderate evidence]
Journal of the American Society of Nephrology 1997: Renal responses to sodium restriction in patients with early diabetes mellitus [randomized trial; moderate evidence] ↩
Even though this was an analysis of multiple trials, they were very small trials and only included a total of 254 individuals.
Cochrane Database of Systematic Reviews 2010: Altered dietary salt intake for preventing and treating diabetic kidney disease [sytematic review of randomized controlled trials; strong evidence] ↩
The Journal of Clinical Endocrinology & Metabolism 2014: Dietary sodium intake and incidence of diabetes complications in Japanese patients with type 2 diabetes: analysis of the Japan Diabetes Complications Study (JDCS) [observational study with HR < 2; very weak evidence] ↩
The Journal of Clinical Endocrinology & Metabolism 1998: Dietary sodium restriction impairs insulin sensitivity in noninsulin-dependent diabetes mellitus [randomized trial; moderate evidence]
American Journal of Hypertension 1999: Moderate dietary salt restriction increases vascular and systemic insulin resistance [randomized trial; moderate evidence]
Hypertension 2014: Effect of low salt diet on insulin resistance in salt-sensitive versus salt-resistant hypertension [randomized trial; moderate evidence]
American Journal of Hypertension 1994: Dietary NaCl restriction deteriorates oral glucose tolerance in hypertensive patients with impairment of glucose tolerance [randomized trial; moderate evidence] ↩
Metabolism 2011: Low-salt diet increases insulin resistance in healthy subjects [randomized trial; moderate evidence]
Clinical Science 2007: Salt intake and insulin sensitivity in healthy human volunteers [observational study; very weak evidence] ↩
When functioning properly, your kidneys reabsorb water, sodium, and other nutrients from your blood as needed and excrete whatever isn’t needed into your urine.
In chronic kidney disease, the kidneys become less efficient at eliminating excess sodium from the body. Additionally, hypertension is a leading cause of kidney failure because increased blood pressure can damage the arteries that lead to the kidneys, as well as the delicate blood vessels inside the kidneys. ↩
Albumin is a protein normally present in blood, and its appearance in urine indicates that the kidneys aren’t functioning the way they should be.
Nutrients 2018: Dietary salt restriction in chronic kidney disease: a meta-analysis of randomized clinical trials [strong evidence] ↩
Journal of the American Medical Association 2016: Sodium excretion and the risk of cardiovascular disease in patients with chronic kidney disease [observational study with HR < 2; very weak evidence] ↩
Open Heart 2014: The wrong white crystals: not salt but sugar as aetiological in hypertension and cardiometabolic disease [commentary; no evidence]
Journal of the American College of Nutrition 2017: Blood pressure regulation: reviewing evidence for interplay between common dietary sugars and table salt [overview article; ungraded] ↩
Diabetes Therapy 2018: Effectiveness and safety of a novel care model for the management of type 2 diabetes at 1 year: an open-label, non-randomized, controlled study [weak evidence]
Diabetes Research and Clinical Practice 2018: Effect of dietary carbohydrate restriction on glycemic control in adults with diabetes: A systematic review and meta-analysis [strong evidence] ↩
Potassium seems to have the same effect on the kidney as a blood pressure medication called a thiazide diuretic.
Transactions of the American Clinical and Climatological Association 2015: Why Your Mother Was Right: How Potassium Intake Reduces Blood Pressure[randomized trial; moderate evidence] ↩
American Journal of Physiology: Endocrinology and Metabolism 2017: Cardiovascular benefits associated with higher dietary K + vs. lower dietary Na +: evidence from population and mechanistic studies[overview article; ungraded] ↩
The flavonoids and polyphenols in certain citrus fruits have been found to have anti-hypertensive effects. This is also the case for magnesium and lactotripeptides in dairy products, as well as omega-3 fatty acids in fish (EPA/DHA) and nuts (ALA).
Journal of Clinical and Experimental Cardiology 2016: Role of Dietary Components in Modulating Hypertension[overview article; ungraded] ↩
PLoS One 2017: Oral potassium supplementation for management of essential hypertension: A meta-analysis of randomized controlled trials [strong evidence] ↩
There is also some benefit seen at potassium intakes just under 3000mg.
Nutrition Today 2018: What Is the Evidence Base for a Potassium Requirement?[overview article; ungraded]
Note that people with kidney disease and those taking medications that can raise blood potassium should not increase dietary potassium before consulting their healthcare provider. ↩
You can test your own blood pressure or look for signs of fluid retention (puffiness, tight rings) the day after you’ve eaten salty foods and compare these results to those following a day of eating less salt. In many cases, fluid retention and elevated blood pressure may be unrelated to sodium intake or only minimally influenced by it. ↩
This is based on the consistent clinical experience of doctors who regularly use low-carb nutrition interventions with appropriate patients.[weak evidence] ↩