17 comments

  1. Boundless
    re: ... with avocado mayonnaise ...

    Is this a commercial product, or do you have a recipe (which I don't find on your blog)?

    An avocado-oil-based mayo just became available in the US (mail-order only, for the moment). I haven't tried it yet. Mayo has been one of the challenging condiments to mimic as LCHF. Most commercial mayos are polluted with junk (principally industrial grain or soybean oils).

    Replies: #4, #17
  2. Karen
    Andreas: Any thoughts on this:http://www.theglobeandmail.com/life/health-and-fitness/health/the-not-so-simple-reasons-for-becoming-vegan/article23123391/
  3. Paul the rat
    Delicious. Although, personally, I would add a splash of horseradish/red beetroot chutney. I love horseradish and, apparently, it is good for you:

    http://www.mdpi.com/1420-3049/19/3/3160

  4. Murray
    Avocado mayonnaise is simple. I have occasion to make some at least once per week. Just put in a ripe avocado together with a surfactant (mustard powder, garlic or egg yolk, depending on what flavour you prefer for that meal), blend, maybe add some lemon or lime juice (again, depending on the dish) and then add a stream of EV olive oil while blending, seasoning to taste. (I use a hand-held immersion blender.) We have this with several meat dishes, and it is especially nice with salmon. It also goes well with vegetables, or to enhance a salad. We prefer this to regular mayonnaise (which I also make at home).
    Reply: #13
  5. Paul the rat
    Nice review
    Clin Nutr. 2015 Jan 23. pii: S0261-5614(15)00035-7. doi: 10.1016/j.clnu.2015.01.013. [Epub ahead of print]

    Toward a cancer-specific diet.

    Bozzetti F1, Zupec-Kania B2.
    Author information

    Abstract
    BACKGROUND & AIMS:
    It is widely acknowledged that the energy metabolism of cancer cells mainly relies on anaerobic glycolysis and this has prompted many researchers to try to reduce the malignant cells growth of experimental tumours through a programme of calorie restriction. Recently this approach has been proposed also to cancer patients. In the meantime it was demonstrated that the effects of calorie restriction on tumour growth are mediated through the toxic effect of ketone bodies on cancer cells which have a defective mitochondrial function, while these substrates are well-utilized by the normal cells.
    METHODS:
    This review analyzes the main available data regarding the tumour growth in patients undergoing a period of starvation or of normal/artificial nutrition as well as the recent approach through special normocaloric ketogenic diets which are well utilized by cancer patients while may be unfavourable for cancer cells.
    RESULTS:
    Despite the paucity of data it appears that modulation of tumour growth by the calorie restriction/nutritional support is unlikekly in humans for several reasons: the different tumour cells growth rate and different tumour/host carcass ratio and duration of treatment, between tumour-bearing animals and patients.
    CONCLUSION:
    There is a large consensus in literature that maintaining a normal body weight and preserving the lean body mass through an adequate nutrition is beneficial in cancer patients. The nutritional approach through a ketogenic diet which may be toxic for the cancer cells while is well utilized and tolerated by the patient seems promising in a next future.

    Reply: #8
  6. Paul the rat
    Int J Biochem Cell Biol. 2015 Feb 7. pii: S1357-2725(15)00032-1. doi: 10.1016/j.biocel.2015.01.022. [Epub ahead of print]
    Mitochondria: The ketogenic diet-A metabolism-based therapy.
    Vidali S1, Aminzadeh S1, Lambert B2, Rutherford T2, Sperl W3, Kofler B4, Feichtinger RG1.
    Author information

    Abstract
    Mitochondria are the energy-producing organelles of the cell, generating ATP via oxidative phosphorylation mainly by using pyruvate derived from glycolytic processing of glucose. Ketone bodies generated by fatty acid oxidation can serve as alternative metabolites for aerobic energy production. The ketogenic diet, which is high in fat and low in carbohydrates, mimics the metabolic state of starvation, forcing the body to utilize fat as its primary source of energy. The ketogenic diet is used therapeutically for pharmacoresistant epilepsy and for "rare diseases" of glucose metabolism (glucose transporter type 1 and pyruvate dehydrogenase deficiency). As metabolic reprogramming from oxidative phosphorylation toward increased glycolysis is a hallmark of cancer cells; there is increasing evidence that the ketogenic diet may also be beneficial as an adjuvant cancer therapy by potentiating the antitumor effect of chemotherapy and radiation treatment. This article is part of a Directed Issue entitled: Mitochondrial Diseases.

  7. KDM
    I wish I could afford rib-eye!
  8. Boundless
    "... support is unlikekly in humans ..."
    "... seems promising in a next future."

    Paul, you copied that abstract accurately. Can you comment on what explains the grammar and spelling? It reads like a poor machine translation.

    Reply: #10
  9. PaleoDentist
    Thank you for the abstracts, just what I needed!
  10. Paul the rat
    Boundless, as you know English language is the accepted language of science. Researchers from non-english speaking countries have to publish in English, there is an ever-increasing number of journal editors whose English is a second language - since the problem. All this does not justify your rightful concern, but sloppiness pops-up with ever increasing frequency.
    (mind you some native English speakers (I am not one of them) could do better as well)
  11. Paul the rat
    Ooo what the heck, I'll stick to the dietary carbohydrate restriction

    Cancer Res. 2014 Dec 1;74(23):6991-7002. doi: 10.1158/0008-5472.CAN-14-0385. Epub 2014 Oct 10.
    Long-chain fatty acid analogues suppress breast tumorigenesis and progression.
    Gluschnaider U1, Hertz R1, Ohayon S1, Smeir E1, Smets M1, Pikarsky E2, Bar-Tana J3.
    Author information

    Abstract
    Obesity and type 2 diabetes (T2D) are associated with increased breast cancer incidence and mortality, whereas carbohydrate-restricted ketogenic diets ameliorate T2D and suppress breast cancer. These observations suggest an inherent efficacy of nonesterified long-chain fatty acids (LCFA) in suppressing T2D and breast tumorigenesis. In this study, we investigated novel antidiabetic MEDICA analogues consisting of methyl-substituted LCFA that are neither β-oxidized nor esterified to generate lipids, prompting interest in their potential efficacy as antitumor agents in the context of breast cancer. In the MMTV-PyMT oncomouse model of breast cancer, in which we confirmed that tumor growth could be suppressed by a carbohydrate-restricted ketogenic diet, MEDICA treatment suppressed tumor growth, and lung metastasis, promoting a differentiated phenotype while suppressing mesenchymal markers. In human breast cancer cells, MEDICA treatment attenuated signaling through the STAT3 and c-Src transduction pathways. Mechanistic investigations suggested that MEDICA suppressed c-Src-transforming activity by elevating reactive oxygen species production, resulting in c-Src oxidation and oligomerization. Our findings suggest that MEDICA analogues may offer therapeutic potential in breast cancer and overcome the poor compliance of patients to dietary carbohydrate restriction.

  12. Andrew
    Chipotle in Sweden?
  13. Apicius
    Thanks for the avocado mayo recipe tip, Murray. You inspired me to make a batch tonight to accompany my beef meatballs with fried mushrooms. And oh my goodness...it was incredibly good! I used an egg yolk and then added some Dijon mustard to counterbalance with the red meat....dang it was good!!
    Reply: #14
  14. Murray
    It's great it worked for you. We always love it. The result to effort ratio is very high.
  15. Gazelle
    Murray- I was wondering since you were so generous in sharing your avocado mayo recipe with us if you would share your regular mayo recipe also. I have been trying to get the courage up to make it fresh but I cant figure out what oil to use to make it. Most of the recipes I read say use something bland tasting not coconut or olive oil - so what does that leave if we are following an LCHF lifestyle?

    Thank you, Gazelle

    Reply: #16
  16. Nicole
    A light olive oil, avocado oil or macadamia oil are the favourites. I use the light olive oil as the others are way too expensive for me to use often.
  17. Trish
    Here's a great mayo that meets all the requirements of LCHF: Chosen Foods Avocado Mayo. It's excellent!

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