I’m a big fan of Ben “Bad Science” Goldacre. This new TED talk by him highlights a huge problem. A “cancer at the core of evidence based medicine”, as Goldacre puts it. We don’t really know if the drugs we use work. We just believe that we know.
Goldacre has just published a book on the subject, called Bad Pharma. You can read the foreword on his blog. I ordered a copy right away.