TV4 på nätet: ”Ny fettbok ger felaktiga kostråd”?
Här är inslaget från Nyhetsmorgon! Komplett med en klassiskt mediahysterisk titel: ”Ny fettbok ger felaktiga kostråd”. Nåväl, kontroverser ökar intresset och folk kan säkert bilda sig en egen uppfattning om vad som verkar vara rätt eller fel.
Kom gärna med positiv OCH negativ kritik. Vad kan jag göra bättre nästa gång?
PS: Jag är 202 cm om någon undrar. Det blir en viss kontrast bredvid mindre förvuxna människor.
Uppdatering: efter ett antal protestmejl bytte TV4 titeln på inslaget till ”Fett – bra eller dåligt?”.
213 kommentarer
Pratet om att hjärnan "föredrar" ketoner tror jag helt enkelt syftar på att hjärnans glukosbehöv minskar när det finns tillgång till ketoner. Någon uttryckte det som att hjärnan föredrar ketoner och sen har det upprepats. Preferens eller nödtvång? Det är nog svårt att veta eftersom det aldrig lär finnas gott om båda ketoner och glukos samtidigt.
Har för mig att det var något om att ketonkroppar tas upp ur blodet 40 ggr lättare än glukos.
http://www.about-axona.com/pdf/prescribinginformation.pdf
"Alzheimer’s Disease as a Metabolic Deficiency
Under normal conditions, glucose is the primary energy source for the brain.
Imaging studies have shown decreased utilization of glucose in the brains of
AD patients early in the disease, before clinical signs of cognitive impairment
occur. This decrease in glucose metabolism (hypometabolism) worsens as
clinical symptoms develop and the disease progresses.1,2 Hypometabolism may
not be solely an artifact of cell atrophy since it occurs in asymptomatic patients
at risk for AD, such as patients homozygous for the epsilon 4 variant of the
apolipoprotein E gene (APOE4, a genetic risk factor for AD), as well as in familial
forms of AD. Thus, AD is a disease with distinctive metabolic and nutritional
requirements.3,4
Given that hypometabolism is an early and progressive event in AD and may
precipitate downstream pathological events, it is reasonable to target the
improvement of neuronal energy states for the management of AD. Studies in
animals and human subjects have shown that increasing blood glucose levels
facilitates memory.5 However, due to the impracticality of maintaining chronically
elevated glucose levels, a safer alternative is required. Ketone bodies provide
an alternative energy substrate that can be utilized by the brain to improve
cognition and memory.
Ketone bodies are naturally produced from fat stores as an alternative to glucose
during periods of sustained hypoglycemia, such as during fasting or very low
carbohydrate intake. In a controlled clinical study in human subjects experiencing
hypoglycemia, the infusion of ketones was shown to improve cognitive function
compared with control subjects, suggesting that increased ketones can
substitute for glucose as an energy source for the brain.6,7
In vitro data indicate that the ketone body b-hydroxybutyrate (BHB) can
substitute for a large fraction of glucose as an energy substrate, and preserves
neuronal integrity and stability.8 Ketone bodies feed directly into the tricarboxylic
acid (TCA) cycle in neurons and generate adenosine triphosphate (ATP), as well
as increasing pools of acetyl-CoA and succinate. Ketones are neuroprotective
against several types of toxic insults,9 and also reduce neuropathological
changes, such as b-amyloid levels in animal models of AD.10"
Mary T. Newport (intervjuaren är importör av kokosolja)
Del 1 http://www.youtube.com/watch?v=iScs0uzQZFk
Del 2 http://www.youtube.com/watch?v=LOrDIixbGMs
Del 3 http://www.youtube.com/watch?v=fIfY-lHDLRk
Del 4 http://www.youtube.com/watch?v=X2jp7BhDFrU
Del 5 http://www.youtube.com/watch?v=Up6JrQhaDUw
Del 6 http://www.youtube.com/watch?v=G-IOs0JE1zg
http://www.coconutketones.com/
"Alzheimer’s Disease as a Metabolic Deficiency
Under normal conditions, glucose is the primary energy source for the brain.
Imaging studies have shown decreased utilization of glucose in the brains of
AD patients early in the disease, before clinical signs of cognitive impairment
occur. This decrease in glucose metabolism (hypometabolism) worsens as
clinical symptoms develop and the disease progresses.1,2 Hypometabolism may
not be solely an artifact of cell atrophy since it occurs in asymptomatic patients
at risk for AD, such as patients homozygous for the epsilon 4 variant of the
apolipoprotein E gene (APOE4, a genetic risk factor for AD), as well as in familial
forms of AD. Thus, AD is a disease with distinctive metabolic and nutritional
requirements.3,4
Given that hypometabolism is an early and progressive event in AD and may
precipitate downstream pathological events, it is reasonable to target the
improvement of neuronal energy states for the management of AD. Studies in
animals and human subjects have shown that increasing blood glucose levels
facilitates memory.5 However, due to the impracticality of maintaining chronically
elevated glucose levels, a safer alternative is required. Ketone bodies provide
an alternative energy substrate that can be utilized by the brain to improve
cognition and memory.
Ketone bodies are naturally produced from fat stores as an alternative to glucose
during periods of sustained hypoglycemia, such as during fasting or very low
carbohydrate intake. In a controlled clinical study in human subjects experiencing
hypoglycemia, the infusion of ketones was shown to improve cognitive function
compared with control subjects, suggesting that increased ketones can
substitute for glucose as an energy source for the brain.6,7
In vitro data indicate that the ketone body b-hydroxybutyrate (BHB) can
substitute for a large fraction of glucose as an energy substrate, and preserves
neuronal integrity and stability.8 Ketone bodies feed directly into the tricarboxylic
acid (TCA) cycle in neurons and generate adenosine triphosphate (ATP), as well
as increasing pools of acetyl-CoA and succinate. Ketones are neuroprotective
against several types of toxic insults,9 and also reduce neuropathological
changes, such as b-amyloid levels in animal models of AD."
Forskningsreferenser finns i slutet på
http://www.about-axona.com/pdf/prescribinginformation.pdf
Del 1 http://www.youtube.com/watch?v=iScs0uzQZFk
Del 2 http://www.youtube.com/watch?v=LOrDIixbGMs
Del 3 http://www.youtube.com/watch?v=fIfY-lHDLRk
Del 4 http://www.youtube.com/watch?v=X2jp7BhDFrU
Del 5 http://www.youtube.com/watch?v=Up6JrQhaDUw
Del 6 http://www.youtube.com/watch?v=G-IOs0JE1zg
http://www.coconutketones.com
http://www.coconutketones.com
Även länkar till Powerpointbilder från föreläsningar.