Happy Ketones

ketones

Here’s low-carb blogger Jimmy Moore at the recent obesity conference. He’s smiling about soon hitting two consecutive years in deep ketosis (and 80 pounds or so lost).

The gadget he’s holding up is a new breath analyzer for acetone (i.e one of the two main ketone bodies). Yellow light means plenty of acetone.

The gadget is $99 and is good for any number of measurements. It seems to work pretty well. Better than urine strips but not quite as good as the gold standard: blood measurements.

You can read more about the Ketonix breath analyzer and order it here.

Disclosure

I have no financial connection to the manufacturer but I have recieved two breath analyzers of my own for testing. The older version seemed to work pretty well. I have not yet tested the updated version – Ketonix Sport – that Jimmy is holding.

Earlier

Final Report: Two Months of Strict LCHF and Ketone Monitoring

Lose Weight by Achieving Optimal Ketosis

45 comments

Top comments

  1. John
    Charles Grashow = Troll!!
    Read more →
  2. sten
    Yes, I see the gray in the beard.
    It is not unusual that people with black hair often become gray in their 30's. ask your barber!
    Hence it is not a good age indicator for all types.
    I stand for my comment and think Jimmy looks swell and I am also pleased that you cannot any longer attack him for his weight.
    He lost the weight at last just through managing his ketosis.

    You probably are not aware of that once a metabolic syndrome (pot or wheat belly) is established it can be very very difficult to remove the last visceral fat that keeps the same condition "alive", often until premature death.

    That's when elevated dawn blood sugar, protein reduction and just ketosis must be added to low carb to regain health..

    It has also been clearly proven that when the bulk of visceral fat is gone, normal blood sugar regulation also resumes. I.e. diabetes 2 then disappears!
    Professor Taylor, Newcastle, UK did it his own way but checked with MRI before and after.
    But as suspected resumption of a standard diet brings the diabetes-2, and weight gain back. A cause and effect almost similar to getting drunk from two much whisky.

    Probably due to that a standard diet today is exceptionally high in fast carbs introduced by mixing sugar in most processed/packaged food and the replacement of old wheat with new wheat that rasies blood sugar quicker than sugar, quietly in the 1980's.

    I note also that both the Swedish LCHF-blog and this English now have attracted several frequent delusionists or killjoys. But it is accepted here and we take equal joy in explaining to you as to other readers here as we do not know the reasons behind your opinions.

    But if you write anything contrary ( like informing about regaining health from different foods) on "patient blogs" , you are quickly moderated away. It happened to me!

    Read more →

All comments

  1. Frances
    "Thumbs up" from me!
  2. sten
    Interesting ! Where is the "approximative conversion table" between breath ketones and blood ?
    If repetitive this is good value compared to keto-sticks.
    BTW Jimmy Moore just looks younger and younger !
    What's goin' on ?
    Reply: #9
  3. Ash Simmonds
  4. bill
    Just ordered one.

    Woooo Hoooo! Been looking forward to this since
    hearing about it.

  5. bill
    Oh, yeah. We just put up the first of the speakers from
    the Central Coast Nutrition Conference. Dr. Eric Westman.

    Here's the link:

    https://www.youtube.com/watch?v=BbwUWNg9M9U&feature=youtu.be

    Hope you like it, and Thank You! to Dr. Eenfeldt for allowing us
    to post our conference plugs on your blog.

  6. Marie lamela
    How do I get the ketosias gadget please send me all the info you can on this diet I have been doing it for two and half months hit a brick wall what am I doing wrong?
  7. Eric Anderson
    I visited the web site for the product and still have questions:

    Blood levels are in 0.5 to 5 mm range after months or years of keto adaptation. Urine strips not so good as urine levels drop off after longer term keto apatation.

    So does the breath ketone level still indicate level of keto adaptation after6 weeks, 6 months, or 6 years?

    If blood is .5 mm what color range would be expected? same for 1.5 mm, 2.5 mm, 4 or 5 mm?

    Has anyone used this for 30 days or more? Am PM 2 hours after meals

    Can I eat a few bites of something like a meat dish that has added sugar and get a quick and effectve warning?

    Looking forward to testing this after 120 carb calorie day with 90 gram of protein versus 6 or less carbs and zero protein with 200 or 100 grams of fat

    Eric

  8. smc
    To Bill:

    Thank you for posting the lecture with Dr. Westman. But why only 240p resolution? This makes it difficult (for me anyway) to read the lettering on the screen.

    Reply: #11
  9. charles grashow
    @Sten

    "BTW Jimmy Moore just looks younger and younger !"

    He's only 42 - with gray hair - how's that looking younger and younger?

    Delusions

    Replies: #10, #12, #14
  10. sten
    Yes, I see the gray in the beard.
    It is not unusual that people with black hair often become gray in their 30's. ask your barber!
    Hence it is not a good age indicator for all types.
    I stand for my comment and think Jimmy looks swell and I am also pleased that you cannot any longer attack him for his weight.
    He lost the weight at last just through managing his ketosis.

    You probably are not aware of that once a metabolic syndrome (pot or wheat belly) is established it can be very very difficult to remove the last visceral fat that keeps the same condition "alive", often until premature death.

    That's when elevated dawn blood sugar, protein reduction and just ketosis must be added to low carb to regain health..

    It has also been clearly proven that when the bulk of visceral fat is gone, normal blood sugar regulation also resumes. I.e. diabetes 2 then disappears!
    Professor Taylor, Newcastle, UK did it his own way but checked with MRI before and after.
    But as suspected resumption of a standard diet brings the diabetes-2, and weight gain back. A cause and effect almost similar to getting drunk from two much whisky.

    Probably due to that a standard diet today is exceptionally high in fast carbs introduced by mixing sugar in most processed/packaged food and the replacement of old wheat with new wheat that rasies blood sugar quicker than sugar, quietly in the 1980's.

    I note also that both the Swedish LCHF-blog and this English now have attracted several frequent delusionists or killjoys. But it is accepted here and we take equal joy in explaining to you as to other readers here as we do not know the reasons behind your opinions.

    But if you write anything contrary ( like informing about regaining health from different foods) on "patient blogs" , you are quickly moderated away. It happened to me!

  11. bill
    smc:

    Yeah, sorry, our tech team is working on it.

  12. Joey B
    Most men I know have grey fascial hair in their 30's
  13. John
    Charles Grashow = Troll!!
  14. Murray
    Hogwash, Grashow. Jimmy obviously looks younger than he did before. Anyone honest can see that. No one claimed he looked young for his age. Jimmy has recovered a lot from metabolic damage to regain a large measure of health. To demean that is to be churlish, Charles.
  15. Eric Anderson
    Second the thank you.

    I enjoyed the reference to the 100 year old book that had the diet for a diabetic pre insulin andhigh carb mainstream.

    150 grams fat
    75 grams protein
    10 grams carbs

    (1350 _ 300 + 40) is in the range of modern ketogenic diets)
    When this worked it is a shame and a sham that it was late ignored much as the ketogenic diet was ignored by the most of the medical epilepsy groups.

    While insulin response varies from person to person and with the same person over time the general observations of carbs, insulin, glucose and health speak for themselves.

    eric

  16. NS
    It would be nice to see more whole truths in this diet debate including but not limited to the following:

    1. There are routes to "dietary ketosis/ketosis" other than LC/LCHF - calorie reduction, intermittent fasting, exercise, filling up on very high fiber, low calorie, low glycemic foods. As such, the terms should not be appropriated and marketed as the exclusive domain of the LC/LCHF movement.
    2. Fish and meat are quite insulogenic; often more so than even some carbohydrate rich foods. I have never seen this discussed in LC/LCHF forums. I wonder why that is the case. For the literature, see Holt's Insulin Index. This may in fact be one reason why a significant number of people have issues on LC/LCHF.
    3. While Jimmy Moore has done reasonably well in acheiving and maintaining a healthy weight, considering where he has come from, he is by no means a paragon of health. His LDL lipoprotein numbers are through the roof high, he seems to have worsened his insulin resistance since in his own words he sees very high blood sugars even from a simple salad, he eats a diet that is composed of 97% protein and fat. Are there any studies on the health or longevity of the Masai or the Inuit? I don't know of any but those Okinawans and other members of the Blue Zones seem to be doing quite well. Lastly, JM does not seem to look particularly young....those Asians on the other hand really do.
    4. All calories inhibit weight loss. Carbs maybe worse than protein/fat, but the latter are not "free" in terms of their effects on weight, or long term health.

    Replies: #19, #27, #39
  17. paleozeta
    @sten; @john
    i am a big fun of jimmy, whit his great interviews he has helped turn my life around.
    the first thought that came into my mind watching this picture is that he looks older than the last picture i saw of him.
    saying what i think does not make me a troll. this is not a battle, it is expressing ones true opinion.
    therefore who points fingers should consider that.
    and more , jimmy is not the subject of the article.
  18. Eddie Mitchell
    "Charles Grashow = Troll!!"

    Too right, and completely batshit !

    Eddie

  19. sten
    Where did you get the figure 97% protein from ?
    Nobody survives such diet for more than a few weeks. Link to Jimmy's page showing this please!

    Also LDL is a meaningless number. Particle number is an accepted higher standard, or apo-B/apo_A which measures number of LDL/HDL particles. Only problem with it is that it 1/ A little more expensive as based on NMR 2/ Statin sales would maybe half as only those with high number of LDL would be left in risk zone. A "little more expensive" is probably offset in first years statin usage reduction. I paid euoro 70 for the quotient and fasting insulin last year. It took my doctor a few weeks to find out where he could get the test done on my request. The biggest hurdle.

    The apo-quotient also has well established risk profile associated with it derived from a world wide cross section of people who had heart attacks. A number of parameters were measured and it was found after comparing each case (over 10,000 heart attacks!) with age matched healthy subjects that this quotient best described the risk.

    Double the quotient = double the risk for heart attack. For LDL by weight there is not even an agreed risk function as higher LDL is preserving life after 60 or so.

    BFN - may return to rest when I have time.

  20. Marcy
    I have been following Jimmy for years and I think he looks terrific. He has done so much for people like me with messed up insulin/metabolism. We are all getting older, that said, he looks fantastic.
  21. NS
    "Where did you get the figure 97% protein from ?
    Nobody survives such diet for more than a few weeks. Link to Jimmy's page showing this please!"

    You are in error, Sten. JM has, nothwithstanding your innocence on the matter, been ~vociferously~ promulgating the virtues of his 83-85%+ fat eating regimen ever since he began his "nutritional ketosis" madness more than a year ago. But isn't it the responsibility of those who advocate high fat diets and defend them publicly on blogs to make themselves familiar with this kind of information already??? Apparently not.

    For your reference, one link, among many:

    http://livinlavidalowcarb.com/blog/jimmy-moores-n1-experiments-nutrit...

    "Of course, I’ve been purposeful in eating a diet that is very high in fat to around 80-85% of calories, moderated in protein to about 10-15% of calories and very low-carb minimizing the intake to 1-3% of calories. My #1 goal has been to reach a ketotic state and not consume anything that would knock me out of that. Of course, when my levels reached the 4.0-5.0 range, I felt I had a little bit of wiggle room to have a little something extra if I wanted it. But over the past week or so the blood ketone levels have settled down naturally staying between 1.0 and 2.0 millimolar–right where it needs to be to give me the benefits of ketosis that I’m looking for."

    Further, you have misread my comments. I said nothing of LDL-c. I specifically talked about his LDL particle numbers being dangerously high, at last count, over 2700.

    You may find the following to your interest. Directly on JM's blog, Dr, Thomas Dayspring wrote the following:

    “Using all the knowledge we possess today, all of the numbers that you are thrilled about have no meaning in the face of a 99th percentile LDL-P. You also should not say an LDL-C of 285 has no meaning. The cholesterol concentrations that often have no meaning are low levels (where an LDL-P is needed to evaluate risk). No one with an LDL-C of 285 with the exception of a Type III dyslipoproteinemia patient have a low apoB or LDL-P. If you have an LDL-C that high, particle testing is not needed. You need to significantly reduce the saturated fat in your diet and see what happens: repeat the NMR in 3 weeks and you will know if your nightmare LDL-P is sat fat related. I’ll bet your LDL-P drops. If it does not, you need serious lipid-modulating medication. We have seen this paradoxical horrific rise in LDL-P in some people who are on ketotic diets.”

    His numbers as of 4/18/13:

    TC 310
    LDL-C 236
    HDL-C 66
    Trigs 38
    LDL-P 2730
    Small LDL-P 478

    And lastly but yet perhaps most significantly I spoke in my original comment about the need for people to speak in "whole truths" rather than bits of information that serve different agendas. JM boasts of the experts, including Dayspring, who is perhaps the world's leading lipidologist, he interviewed for the "Cholesterol Clarity" manifesto he wrote. Yet, strangely, the book dedicates only a line or two to Dayspring and very conveniently excludes the quote from above from JM's blog and the one below:

    http://www.lecturepad.org/dayspring/lipidaholics/pdf/LipidaholicsCase...

    "Let’s get rid of the nonsense seen all over the internet that atherosclerosis is an inflammatory disease, not a cholesterol disease. That is baloney-with the reality being that it is both. One cannot have atherosclerosis without sterols, predominantly cholesterol being in the artery wall: No cholesterol in arteries – no atherosclerosis. Plenty of folks have no systemic vascular inflammation and have atherosclerotic plaque. However clinicians have no test that measures cholesterol within the plaque – it is measured in the plasma. It is assumed, that if total or LDL-C or non-HDL-C levels are elevated the odds are good that some of that cholesterol will find its way into the arteries, and for sure there, are many studies correlating those measurements with CHD risk. Yet, we have lots of patients with very low TC and LDL-C who get horrific atherosclerosis. We now recognize that the cholesterol usually gains arterial entry as a passenger inside of an apoB-containing lipoprotein (the vast majority of which are LDLs) and the primary factor driving LDL entry into the artery is particle number (LDL-P), not particle cholesterol content (LDL-C). Because the core lipid content of each and every LDL differs (how many cholesterol molecules it traffics) it takes different numbers of LDLs to traffic a given number of cholesterol molecules: the more depleted an LDL is of cholesterol, the more particles (LDL-P) it will take to carry a given cholesterol mass (LDL-C). The usual causes of cholesterol depleted particles are that the particles are small or they are TG-rich and thus have less room to carry cholesterol molecules. Who has small LDLs or TG-rich LDL’s? – insulin resistant patients! After particle number endothelial integrity is certainly related to atherogenic particle entry: inflamed endothelia have inter-cellular gaps and express receptors that facilitate apoB-particle entry. So the worse scenario is to have both high apoB and an inflamed dysfunctional endothelium. Is it better to have no inflammation in the endothelium – of course! But make no mistake the driving force of atherogenesis is entry of apoB particles and that force is driven primarily by particle number not arterial wall inflammation."

    Reply: #23
  22. NS
    @Sten
    In case you are not familiar with Dayspring, I would direct you to these:

    https://www.youtube.com/watch?v=hRoxvI1p1Bc

    https://www.youtube.com/watch?v=ceIQY4QRZYI

    https://www.youtube.com/watch?v=an6L9VY0v8A

    And, incidentally, if anyone is interested, I would still like to know, as I mentioned in my first comment above, the seeming reason/s meat, fish, and dairy proteins are absent from the conversation on LC/LCHF forums even though they elicit high insulin responses, sometimes higher than even some carb rich foods.

    http://ajcn.nutrition.org/content/66/5/1264.long

    http://web.healthorize.com/gi_insulin_index.htm

    See from the 40:38 mark:

    https://www.youtube.com/watch?v=ZbnshVO4PRM.

    Replies: #24, #29
  23. FrankG
    While a diet that is...

    "...very high in fat to around 80-85% of calories, moderated in protein to about 10-15% of calories and very low-carb minimizing the intake to 1-3% of calories."

    ...MIGHT be described as...

    "...composed of 97% protein and fat"

    ...I can certainly think of less misleading ways... so much for your enthusiasm for examining "whole truths" :-P

    ---

    "...Dayspring, who is perhaps the world's leading lipidologist..."

    According to who exactly? I don't respond favourably to an appeal to authority... not impressed.

  24. FrankG
    "...I would still like to know, as I mentioned in my first comment above, the seeming reason/s meat, fish, and dairy proteins are absent from the conversation on LC/LCHF forums even though they elicit high insulin responses..."

    Because LCHF is a low-carb high-FAT way of eating... there is no reason to increase protein intake. As you just demonstrated with your quote from Jimmy Moore.

    You do seem to be fixated on protein...

  25. Welldun
    ...looks like another troll has joined us...
    Reply: #26
  26. Paul the rat
    When rats or mice experimental diet is lacking some nutrient, the animals display so called unsettled behavior. They dig in floor littering, are restless all the time as if searching for something, are aggressive to each other and so on and so forth. I see the same behavioral patterns in vegetarian/vegan trolls - their blogs are obviously lacking in something. Pharma-trolls on the other hand, as we all know, well, they have different agenda and behavior.
  27. Paul the rat
    @NS

    "...calorie reduction, intermittent fasting, exercise, filling up on very high fiber, low calorie, low glycemic foods…."

    that is starving oneself to the point of giving-up.

  28. NS
    Yet somehow the formerly morbidly obese people below - along with many others listed in the National Weight Loss Registry - have done exactly that - and kept it off long term. LCHF is one available tool in the war and it may even be a good one. But it has no monopoly on "ketosis."

    https://www.youtube.com/watch?v=ZBXeeIbHUqg

    https://www.youtube.com/watch?v=CEAeVELpOEE
    http://edition.cnn.com/2011/HEALTH/04/22/weight.loss.anita.mills/

    https://www.youtube.com/watch?v=0AqgchcAMNE

  29. sten
    THis is was Jimmy Moore writes on the link.
    " Of course, I’ve been purposeful in eating a diet that is very high in fat to around 80-85% of calories, moderated in protein to about 10-15% of calories and very low-carb minimizing the intake to 1-3% of calories."

    Only reason I can see to mix up Jimmies clear statements by writing 97% protein and fat is to confuse, or be confused.

    The macronutrient ratio is a perfectly balanced ketosis diet. Nothing for daily cereal and bread eaters.

    I saw no reference in Jimmies text to high blood sugar from salad, but his maximum BS over 30 days shown was 110..., extremely good. What are you complaining over?

    You seem to just want to trash Jimmy. I don't see why as he is doing really great, showing others the ins and outs of getting out of weight gain into weight loss and loss of the killing visceral fat , the fat that spawns weight gain and diabetes 2.
    Many cheers to Jimmy !
    My 5 cents!

  30. NS
    Nonsense on top of further nonsense.

    Do you have any links on the longevity of the Masai or Inuit or other LCHF-like eating societies? If so, please share.

    Reply: #35
  31. Nan
    I will definitely invest in the Ketonix as soon as I finish my batch of BK strips. The strips are very expensive, and occasionally one doesn't work, so that is even more irritating.

    http://www.sugaraholics.com
    http://highfatlowcarbrecipes.wordpress.com/

  32. Eric
    What is the NS agenda?

    You wrote about other diet means to achieve Nutritional ketosis

    What insulin levels? Glucose? Blood ketones? HDL? TRI? etceera

    Hungar is a factor in any longterm diet; so what is the hunger response.

    Seems all reports of LCHF with modrate protein avoid the hunger problem.

    Read some more on insulin!!!

    Have you read the Taubes books? Richard K Bernstein?

    is this a hidden vegan or vegan like ploy?

    Ar you promoting Sugar and or grain?
    Starvation diets?

    IF can be or can not be LCHF so what is the response?

  33. murray
    So what if protein results in an insulin release. Take the 70-20-10 fat-protein-carb diet Dr. Cate Shanahan uses. If the protein is comparable to the carbs in insulin index, then just 30% of the diet intake is causing insulin surges. That is a heck of a lot less insulin than on a high carb low fat diet. I can tell modest protein is not an insulin issue from measuring blood ketones, which are a good proxy for absence of insulin. This morning I was 3.6 mmol/L glucose and 2.4 mmol/L ketones. Obvious the protein is not elevating insulin.

    People forget we are talking about biology. Everything is about rates in biology. So the rate and intensity of insulin surges at 70-20-10 (30% insulin triggering) is qualitatively much different than at 20-15-65 (80% insulin triggering). To suggest otherwise is churlish hogwash. Dr. Kenyon's work showed reduced insulin remarkable decreased aging, but as usual there was a J-curve, so no one is aiming for zero insulin.

    And there are numerous metabolic benefits to having less glucose being trafficked in the blood and being shunted into cells, to many to mention in one comment. I have yet to measure my blood glucose above 5.2 mmol/L (94 mg/dL) at any time of day or after any meal since I got my monitor a couple of years ago. Then there are the benefits of ketones as more efficient, mitochondria-enhancing fuel and highly beneficial metabolic signalling.

    As to methods of getting into ketosis without LCHF, surely fasting is LCHF. The body is running off body fat, which is plainly low carb, high fat. Indeed, I recall reading Phinney and Volek pointing out there is autophagy of depleted adipose cells. So, with triglycerides say having 3 c:16 fatty acids and a C3 glycerol, and there being protein from the autophagy, I expect one gets to something near 80-15-5 calories--right near where Jimmy is.

    As to Dr. Dayspring, he is plainly ahead of most of the lipid experts. However, the evidence he marshals for the LDL-P argument is statistically arcane at best and does not establish causation. When I reviewed his site last year he conceded that the case of high LDL on keto is new territory. Here he reverts to old prejudice on the basis it has not been proven safe--"just take the damn statins." In the end, I don't find he has made a persuasive case. The "gradient" hypothesis about more LDL magically penetrating artery walls as if by osmosis is unconvincing. A friend who is an anesthesiologist sees a lot of operations and, for example, gives an example of a lifelong vegetarian with rock bottom LDL with one heart artery totally blocked and the others totally clear. As if by osmosis? I'll go by actual observation over arcane statistics. If the gradient hypothesis were plausible, there would not be one artery blocked and the others clear.

    As for Inuit and the Maasai, Dr. Weston Price in the 1930s surveyed traditional cultures around the world who were not yet introduced to Western diet (notably starch and sugar). Price found the Maasai (who live almost entirely on meat, dairy and blood of ruminants) and certain remote Swiss villagers to be the healthiest he found. The Inuit were healthy, but I expect their extreme habitat confounds longevity comparison. Also, they spend a lot of time in small enclosed spaces (igloos) with lots of smoke, so again, there are confounding factors.

  34. AC
    @NS

    I signed up for the National Weight Control Registry after having lost 100 pounds with LC and keeping it off for over 3 years. LC was not listed as one of the answers to the question about strategies used to lose weight. I never completed the survey because I couldn't explain how I had lost weight. I wonder how many other LCers have never turned in the survey.

    Replies: #36, #37
  35. sten
    Sorry NS, but as far as several others including myself can judge you are a new troll here on the blog. Consequently I will not read or respond to your posts again.
  36. Nan
    @AC - Had the same experience. They only want to hear what they want to hear.
  37. MerryKate
    FWIW, I just recently signed up for the National Weight Control Registry, and they're now including low-carb diets as one of the possibilities on their survey. If it's been a while since you signed up, please do it again - we need to get the message across to them that a low-carb diet is more effective for long-term weight loss and maintenance than a low-fat diet.
  38. Kat
    Grey hair and the timing of grey hair is genetically determined and has nothing at all to do with general health. I am a brunette, older than Jimmy and I have almost no grey hair - but then my father's family goes grey in their mid-60's. My husband, who is the picture of health (so good that doctors often want a detailed account of what exactly he's doing), with a body a Greek god could only envy is a little younger than Jimmy and has almost as much grey hair as Jimmy.
    Reply: #40
  39. Kat
    NS,

    There are many ways of eating available to people. Nutrition really should be highly personalized. That said, you haven't a leg to stand on when you say that LCHF may not be a very good tool.

    As studies performed by Jeff Volek show, study subjects' response to a ketogenic diet are pretty uniform. As carbohydrates are added back into the diet, the variance of responses grows. Some people are very much adapted to carbohydrates and some people are very much less so and the variance among them grows as the level of carbohydrate grows. It seems that thriving on a low carbohydrate diet is a highly conserved trait. That implies it's actually a pretty darn good method.

    For another instance, in at least one study, all subjects lost a similar amount of weight on a calorie restricted LCHF diet. However on a low fat high carb calorie restricted diet the subjects who were less sensitive to insulin lost only a third of the weight subjects who were sensitive to insulin lost. Huge difference.

    How much of any macronutrient a person can consume healthfully is highly individual and depends on their particular parameters. There are people who cannot go below 100 grams of carbs per day (I'm thinking of a particular endurance athlete) and there's me who is an endurance athlete and I do better between 30 and 80 grams even in grueling 3 hour workouts. I have been pouring carbs down my throat at the behest of sports nutritionists all my life to worsening effect (pooh! You're an endurance athlete! You MUST eat no fewer than 200 grams per day as a bare minimum!). In light of these enormous differences between people's genetics and particular medical conditions, your judgement of LCHF's relative value is utterly meaningless.

  40. Murray
    Well if greying is genetically determined, then my genetics are dietarily determined. Six or seven years ago I started greying and I reversed it by following what Dr. Thomas Seyfried calls mitochondrial enhancement therapy, with is essentially calorie restricted low carb high fat. To this day, if I get a few grey hairs on my chest or head I simply cut out carbs and reduce calories for a couple of days and the grey hairs restore to normal. Many others have reported this.

    The problem with the genetic determinism hypothesis is that it does not explain the metabolic mechanism. With diminished mitochondrial output due to oxidative stress, for example, the cells lack sufficient energy to produce pigment. So restoring mitochondrial efficiency restores pigment production. After speaking with several older people with seemingly preternatural non-greying, my wife hit upon low or zero sugar consumption as a near-universal among the non-grey people. Perhaps genetics predisposes some to eat sugar and others not. Excessive sugar burning increases oxidative stress and impairs mitochondria, so the correlation is plausible.

  41. Kat
    Murray,

    Study after study has shown no correlation between greying hair and what people commonly believe greys hair. I'm not sure LCHF vs HCLF has been studied as a factor in greying hair (I doubt it). so, there's really no study that supports your hypothesis and, anecdotally, I know a guy who is 43, does the LCHF and is a fantastic physical specimen, but he's totally grey. My family was decidedly NOT LCHF and nobody has grey hair until their late 50's and few are fully grey until 70. But, anecdotes shouldn't be mistaken for data.

    That said, whether it helps your hair or not, there are very good reasons to follow an LCHF diet. The fact that it has shown in studies (good ones) to lower inflammation and decrease the triglyceride/HDL ratio alone is worth it! If future studies show a positive effect on greying hair, then that's just a bonus!

    Reply: #42
  42. murray
    An n=1 study is very helpful when I am the n=1. It is like an elimination diet. Eliminate the suspected source and if the condition disappears, then reintroduce the source and see if it comes back. If so, the suspected source probably has a causal role. Thus I have high confidence what greying indicates, or at least how to control it.

    Another instructive case for me was the plight of an owner of a small gas and service station. He had recently acquired the station, but it was obvious to my wife and I that it was a poor location for access reasons. He was extremely eager at the beginning and did all sorts of creative things to draw traffic and we made a point of going there often. Sadly, he just could not get the volume he needed. You could see it wearing him down and then he had an inadvertent environmental issue. (A contractor working next door asked to move some large rocks which neither knew would violate fishery regulations.) He asked my wife to act for him to bring a lawsuit for easement access over a neighboring car dealership that had blocked the access easement just before the owner had bought the service station. Anyway, within a few months of things going badly and him looking entirely defeated, he went from jet black hair to totally grey. It was so sad. Plainly it was the stress, which is again consistent with weakened mitochondria as the metabolic mechanism behind loss of capacity to produce pigment in hair cells.

    Do you have reference to a study that shows the mechanism involved in greying of hair? Observational studies without identifying underlying metabolic mechanisms carry very little weight.

  43. Kari
    Question about the ketone breath analyzer. I checked the website and the 2015 models are running 149 dollars. Do you know where I could order the older model or if anyone else makes these a little cheaper? I know that the blood monitoring isn't for me.
  44. Link Bass
    Way better off using blood until this technology improves.
  45. Hazel
    I just read in THE ART AND SCIENCE OF LOW CARBOHYDRATE LIVING (Volek and Phinney) that Jimmy Moore took off 180 pounds (one hundred and eighty): page 282 in my paperbound 2011 copyright edition.

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