12 comments

  1. laza
    Nah, nothing special. Boil anything more complex then water, healthy or not, keep it on the stove some more, you'll end up with ugly looking stuff.

    Maybe it would be a bit more interesting if he boiled Diet Coke.

  2. Michael
    I agree with laza. And it reminds me of the way vegans confirm each other in their (false) belief of how disgusting meat is by showing pictures of suffering animals; not relevant.
  3. erdoke
    A lot of people are unaware of the amount of sugar loaded into a single bottle of coke. Showing that the experiment is just fine.
    On the other hand the infamous New Coke contained even more sweetener and blind testers clearly preferred it over "Classic", but in the end it still sucked emotionally and subsequently disappeared.
    Reply: #8
  4. Paul the rat
    Grains, bananas and grass eating people say that primary cause of diabetes type 2 is the damage of beta cells by dietary fat.
    http://diabetes.diabetesjournals.org/content/52/3/581.full.pdf
  5. Paul the rat
    Diabetes Care. 1990 Jun;13(6):610-30.
    Glucose toxicity.
    Rossetti L1, Giaccari A, DeFronzo RA.
    Author information

    Abstract
    Glucose toxicity is a well-established entity that has been shown in animal models of diabetes to contribute to development of insulin resistance and impaired insulin secretion. In type II (non-insulin-dependent) diabetes in humans, a considerable body of evidence has accumulated indicating that a chronic physiological increment in the plasma glucose concentration leads to progressive impairment in insulin secretion and may contribute to insulin resistance as well. The precise biochemical mechanism(s) responsible for the hyperglycemia-induced defect in insulin secretion remains to be defined but may be related to a defect in phosphoinositide metabolism. In animal models of diabetes, development of insulin resistance is related to downregulation of the glucose-transport system, and a similar phenomenon is also likely to occur in humans. In addition, hyperglycemia in humans may lead to a defect in glycogen synthesis. In this respect, humans may be different from rats. In type I (insulin-dependent) diabetic patients who are poorly controlled, insulin resistance is a characteristic feature and can be ameliorated by tight glycemic control, suggesting that hyperglycemia is responsible for the insulin resistance. Evidence also has accumulated to implicate glucose toxicity in the functional impairment in insulin secretion that occurs during the initial presentation of patients with type I diabetes, and this may explain the honeymoon period so commonly observed after the institution of insulin therapy.

  6. Paul the rat
    Sci. STKE, 31 January 2006
    Vol. 2006, Issue 320, p. tw40
    [DOI: 10.1126/stke.3202006tw40]

    EDITORS' CHOICE

    TRANSCRIPTION
    Why Excess Glucose Is Toxic

    High concentrations of glucose can be toxic and contribute to diabetic retinopathy, for example. Elevated glucose increases glycolytic flux, which leads to increased production of a highly reactive dicarbonyl, methylglyoxal. Cells eliminate this potentially toxic degradation product by enzymatic conversion to lactate by glyoxylase I (GLO1), glyoxylase II, and glutathione. However, in pathological situations, such as diabetes, or conditions of oxidative stress, methylglyoxal may accumulate and react with DNA or arginine, lysine, or cysteine residues of proteins. Yao et al. show that exposure of retinal Müller cells (rMC-1) to elevated glucose increased the concentration of methylglyoxal and stimulated expression of the angiopoietin-2 (Ang-2) gene. Both of these effects were prevented if the cells were overexpressing GLO1, the mitochondrial uncoupling protein UCP-1, or manganese superoxide dismutase (MnSOD). Promoter analysis defined a glucose-response element in the Ang-2 promoter at the Sp1 site, and chromatin immunoprecipitation experiments revealed that the binding of Sp1 was enhanced under conditions of high glucose, whereas Sp3 binding was decreased, suggesting that glucose triggers a switch in these two transcriptional regulators. Overexpression of GLO1, UCP-1, or MnSOD prevented this glucose-stimulated switch. Sp3 coimmunoprecipitated with the corepressor mSin3A. Elevated glucose increased the methylglyoxal modification of mSin3A and increased the association of mSin3A and Sp3 with O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT), resulting in O-GlcNAc modification of Sp3. Inhibition of O-GlcNAc modification of proteins by antisense RNA against the rate-limiting enzyme in UDP-GlcNAc formation or by overexpression of an enzyme that removes O-GlcNAc prevented the switch in Sp1 and Sp3-mSin3A at the Ang-2 promoter. These results provide a mechanism for diabetic retinopathy associated with high glucose, because an imbalance in angiogenic signals (elevated Ang-2 without sufficient vascular endothelial growth factor, for example) can lead to endothelial cell death and regression. These results also have implications for the role of glucose in aging and cancer through the actions of methylglyoxal on transcription (see Ramasamy et al.).

    D. Yao, T. Taguchi, T. Matsumura, R. Pestell, D. Edelstein, I. Giardino, G. Suske, N. Ahmed, P. J. Thornalley, V. P. Sarthy, H.-P. Hammes, M. Brownlee, Methylglyoxal modification of mSin3A links glycolysis to angiopoietin-2 transcription. Cell 124, 275-286 (2006). [PubMed]

  7. Boundless
    > ... the infamous New Coke contained even more sweetener
    > and blind testers clearly preferred it over "Classic", ...

    The fundamental marketing errors that Coke made there were:
    1. forgetting that customers don't buy the product double-blind, and
    2. tampering with the metaphor, as there's no real reason to buy it all

    A can of pop contains nothing that anyone needs.

    You actively want to avoid the sugar, which is often HFCS these days.

    You don't need the acid load from the phosphoric acid and carbonation.

    You don't need whatever might be in the caramel color, or other "natural flavorings" for which details are not disclosed.

    You want to avoid any BPA in the plastic bottle or plastic liner of the can.

    If the water is from municipal sources, you don't need the fluoridation for dental health (if you are grain-free LCHF), and you may even want to avoid it for thyroid health.

    In the specific case of Coca Cola in the US, you don't need the denatured cocaine.

    You don't need the caffeine, although it may be the safest ingredient present.

  8. GP
    If you boil coke then you can inject it. Otherwise you have to snore it :) Not sure how it fits the LCHF lifestyle but it's one helluva drug.
  9. erdoke
    UI study finds diet drinks associated with heart trouble for older women
    http://now.uiowa.edu/2014/03/ui-study-finds-diet-drinks-associated-he...
  10. fouziya
    See waht happen when you boil coke, you can see the end product - the sugar or sucrose the detains at the bottom in a thick consistence... This is what we consume when we drink coke.
    https://www.youtube.com/watch?v=Xtc0rdciJm4
  11. Gotucky
    I have to say, I was disappointed to see dietdoctor post this. There has been an endless stream of scare tactics and pseudo-science surrounding food lately, and I find this viral video to be part of that category. Have you ever seen how caramel is made? Boiling sugar. And when you burn sugar/HFCS and add food coloring and other crap... Voila. LCHF is real, legit science. Sodas are garbage. We don't need to resort to some basement experiment to show the world that eating real food is the only way to live... I mean REALLY live!

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